To HLA activates endothelial exocytosis, releasing VWF and externalizing P-selectin, which | D1T
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To HLA activates endothelial exocytosis, releasing VWF and externalizing P-selectin, which lead to platelet aggregation and leukocyte infiltration. Discussion The major finding of this study is that antibody to HLA activates endothelial exocytosis in vitro and in vivo. These data suggest that one mechanism for antibody injury to transplanted organs is through antibody-triggering endothelial cell e
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