By equivalent TALE fusions (Figures 3, 4 and 7). This may relate to the | D1T
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By equivalent TALE fusions (Figures 3, 4 and 7). This may relate to the relatively low affinity of Bat1 for BEBat1 (Figure 2B) compared to known affinities of TALEs for their natural target boxes. However, the TALE platform has been optimized over several years. The creation of high activity TALE-nucleases, in particular, has been a focus of many labs. Thus, with further work to improve activity,

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